 |
|
|
|
GARLIC TINCTURE (tinctura Allium sativum) from AMAZON HERBS® |
Overview Garlic has long been used in cooking and is known for its medicinal applications. It is currently often used as an antithrombotic and antioxidant herb to help prevent heart disease, atherosclerosis, and cancer. It is promoted for reducing high cholesterol (reduces the clotting tendency of platelets) and blood pressure levels. May also be used against over-activity of the intestine and to improve the immune system. Garlic’s antibiotic action is well-known and is useful for chest infections and colds; kills many types of bacteria, viruses, fungi and parasites. Constituents Active, organic sulfur compounds (S-alkylcysteine sulfoxides, derivatives of the amino acid cysteine such as alliin (S-allyl-L-cysteine sulfoxide). Allicin (diallyldisulfideS-oxide); Ajoene (an unsaturated sulfoxide disulfide). There are also other compounds in Garlic; to date over 100 compounds have been identified in garlic preparations. Pharmacology Allicin, an active principle of freshly crushed garlic has several antimicrobial activities. In its pure form it was found to exhibit antibacterial activity against a wide range of Gram-negative and Gram-positive bacteria, including multidrug-resistant enterotoxicogenic strains of Escherichia coli; antifungal activity, particularly against Candida albicans; antiparasitic activity, including some major human intestinal protozoan parasites (Entamoeba histolytica and Giardia lamblia); and antiviral activity. The main antimicrobial effect of allicin (diallyl thiosulphinate) is due to its chemical reaction with thiol groups of various enzymes. Alliin is the primary ingredient found in garlic. After garlic is crushed, alliin is converted into allicin, the compound that gives garlic its strong smell and numerous health benefits. Garlic has been reported to protect against cardiovascular disease by reducing serum cholesterol concentrations and blood pressure and by inhibiting platelet aggregation. Further, garlic has antioxidant properties. Antioxidants help to destroy free radicals. Ajoene (an unsaturated sulfoxide disulfide), is the principal chemical responsible for garlic's anticoagulant properties. It is a component of allicin, a sulfinyl compound that gives garlic its strong odor and flavor. It is currently being developed as a pharmaceutical for the treatment of blood clotting disorders. This potent phytochemical might reduce the risk of stroke and heart disease. Topic application of ajoene has produced significant clinical response in patients with skin basal cell carcinoma. It was shown to inhibit proliferation and induce apoptosis of several human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-1. Some studies report that topical application of garlic may help in fungal skin conditions (Tinea cruris, Tinea corporis). Dosage Tincture: 1 - 3 ml. (1 - 3 full pipettes) daily. Precaution Garlic has a mild blood thinning- and laxative effect. When using anti-coagulant drugs (Warfarin, Coumadin®, Heparin®, Lovanox®, and Plavix® Aspirin), avoid high doses. Avoid also high doses when pregnant. Garlic intolerance may result in heartburn. Reference Antimicrobial properties of allicin from garlic. Ankri S., Mirelman D. Dept of Biological Chemistry, Weizmann Institute of Science, Rehovot 76100, Israel. Dietary Supplementation with Aged Garlic Extract Inhibits ADP-Induced Platelet Aggregation in Humans¹ Khalid Rahman² and David Billington School of Biomolecular Sciences, Liverpool John Moores University, Liverpool L3 3AF, UK Garlic: The Science and Therapeutic Application of Allium sativaum L and Related Species, 2d ed. Koch HP, Lawson LD, eds., Baltimore: Williams and Wilkins, 1996. The antiatherosclerotic effect of Allium sativum. Atherosclerosis 1999; 144: 237-249. Koscielny J, Klüssendorf D, Latza R, Schmitt R, Radtke H, Siegel G, Kiesewetter H. American Journal of Medicine (June 1994;94:632-5). Jain AK. Hypertension and hyperlipidemia: Garlic helps in mild cases. British Journal of Clinical Practice Symp 69 (Suppl.): 3-6, 1990. Auer W, et al. Effects of garlic powder and garlic oil preparations on blood lipids, blood pressure and well being. British Journal of Clinical Res 6: 91-100, 1995. Santos OS de A, et al. Allium vegetables and reduced risk of stomach cancer. Journal of the National Cancer Institute; 1989; 81: 162-164. You W-C, Blot WJ, Chang y-S, et al. Vegetables, fruit, and colon cancer in the Iowa Women's Health Study. American Journal of Epidemiology; 1994; 139(1): 1-15. Steinmetz KA, Kushi LH, bostick RM, et al. Garlic supplementation and lopoprotein oxidation susceptibility. Lipids 1993; 28 (5); 475-577. Phelps S, Harris WS. Garlic compounds protect vascular endothelial cells from oxidized low density lipoprotein-induced injury. Journal of Pharmacy and Pharmacology; 1997; 49: 908-911. Ide N, Lau BHS. Garlic and its significance for the prevention of cancer in humans: A critical review. British Journal of Cancer 1993;67:424-29. Dorant E, van der Brandt PA, et al. Effect of garlic on total serum cholesterol. A meta-analysis. Annual of Internal Medicine 119(7) Part 1: 599-605, 1993. Warshafsky S, et al. Garlic, onion and cardiovascular risk factors: A review of the evidence from human experiments with emphasis on commercially available preparations. British Journal of Clinical Pharmacology 1989; 28:535-44. Kleijnen J, Knipschild P, Ter Riet G. The above presentation is for informational and educational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage. For many of the conditions discussed, treatment with prescription or over - the - counter medication is also available. Consult your doctor, practitioner, and / or pharmacist for any health problem and before using dietary supplements or before making any changes in prescribed medications. |
| Buy 6 bottles save 10%; buy 12 bottles and save 15%! |
| | ||||
| Item | Description | Unit | Price | Quantity |
| | ||||
| Allium sativum | bulb tincture | 1 oz fl (29.6 cc) | US$ 10.55 | |
| Allium sativum | bulb tincture | 6 x 1 oz fl | US$ 56.97 | |
| Allium sativum | bulb tincture | 12 x 1 oz fl | US$ 107.61 | |
| Allium sativum | bulb tincture | 2 oz fl (59.1 cc) | US$ 19.45 | |
| Allium sativum | bulb tincture | 6 x 2 oz fl | US$ 105.93 | |
| Allium sativum | bulb tincture | 12 x 2 oz fl | US$ 198.39 | |
|
For the right freight rate, please visit our Webstore page! |
| TROPILAB® INC copyright disclaimer |